Work Package 1 – Cross-sectional study of vertebral fracture prevalence and musculoskeletal health

Recruitment is complete in Zimbabwe, South Africa and The Gambia.

Assessment of vertebral fractures (the primary outcome) and bone mineral density and sarcopenia (reduced muscle strength), secondary outcomes, are actively underway. Embedded analyses and papers on Healthy Ageing (intrinsic capacity impairments) and wealth measurement have been drafted.

The first results from Work package 1 which investigated associations between HIV, frailty and health-related quality of life (HRQoL) is published in PubMed: Prevalence, factors and quality of life associated with frailty and pre-frailty in middle-aged and older adults living with HIV in Zimbabwe: A cross-sectional study.